Gabriel Nunez
University of Michigan Medical School, , United States
- This delegate is presenting an abstract at this event.
Gabriel Nuñez earned his M.D. degree from the University of Seville, Spain. He received postdoctoral training in Immunology at the University of Texas Southwestern Medical Center, Dallas (1979–1984) and residency training in Anatomical Pathology at Washington University in St Louis (1985–1990). In 1987, he joined the laboratory of Stanley Korsmeyer at Washington University, where he studied the function of the anti-apoptotic protein Bcl2. In 1991, he joined the Department of Pathology at the University of Michigan in Ann Arbor as an Assistant Professor and was promoted to full Professor in 2001. He holds the Paul de Kruif Endowed Professorship in Academic Pathology. His laboratory identified NOD1 and NOD2, the first members of the Nod-like receptor (NLR) family, a class of pattern-recognition receptors that mediate cytosolic sensing of microbial organisms. Nuñez and colleagues showed that genetic variation in NOD2 is strongly associated with susceptibility to Crohn's disease. Currently, the Nuñez laboratory is interested in microbial-host interactions, the pathogenesis of inflammatory disease and the role of the microbiota in host defense and colitis. Dr. Nuñez is the author of more than 300 scientific publications. His research program is supported by grants from the National Institutes of Health, the Crohn’s and Colitis Foundation of America and the Bill and Melinda Gates Foundation.
Presentations this author is a contributor to:
Linking Pathogen Virulence, the Microbiota and Immunity (#S-18)
11:30 AM
Gabriel Nunez
Concurrent Symposia 2 The microbiome and mucosal immune responses
MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases (#30)
3:00 PM
Rebecca C Coll
Concurrent Mini-Symposium 1