The role of IFN-γ and IL-27 for Th17 plasticity in mouse CNS inflammation — ASN Events

The role of IFN-γ and IL-27 for Th17 plasticity in mouse CNS inflammation (#105)

Florian Wanke 1 , Sonja Moos 1 , André P Heinen 1 , Stephanie Firmenich 1 , Werner Müller 2 , Ari Waisman 1 , Florian C Kurschus 1
  1. University Medical Center of the Johannes Gutenberg-University, Mainz, Germany
  2. Faculty of Life Sciences, Manchester, UK
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  1. Kurschus et al., Genetic proof for the transient nature of the Th17 phenotype. Eur J Immunol. 2010;40:3336-3346
  2. Lexberg et al., IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells. Eur J Immunol. 2010; 3017
  3. Hirota, K. et al. (2011). Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol 12, 255-263.